Thymidine phosphorylase/platelet-derived endothelial cell growth factor is upregulated in advanced solid types of gastric cancer
β Scribed by Yoshikawa, T; Suzuki, K; Kobayashi, O; Sairenji, M; Motohashi, H; Tsuburaya, A; Nakamura, Y; Shimizu, A; Yanoma, S; Noguchi, Y
- Book ID
- 110001044
- Publisher
- Nature Publishing Group
- Year
- 1999
- Tongue
- English
- Weight
- 209 KB
- Volume
- 79
- Category
- Article
- ISSN
- 0007-0920
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We have investigated the expression of platelet-derived endothelial-cell growth factorkhymidine phosphorylase (PD-ECGF/dThdPase) in human breast-cancer tissues by the immunocytochemical method using anti-PD-ECGF/ dThdPase monoclonal antibody. Out of I00 invasive-ductal-carcinoma tissue samples, 39 (
## Abstract ## BACKGROUND Thymidine phosphorylase (TP) is identical to plateletβderived endothelial cell growth factor (PDECGF) and has angiogenic activity. Little is known about the significance of TP/PDECGF activity in patients with renal cell carcinoma (RCC). The authors examined the enzymatic