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Localization of non-specific X-linked mental retardation genes

✍ Scribed by Kerr, Bronwyn ;Gedeon, Agi ;Mulley, John ;Turner, Gillian


Publisher
John Wiley and Sons
Year
1992
Tongue
English
Weight
731 KB
Volume
43
Category
Article
ISSN
0148-7299

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πŸ“œ SIMILAR VOLUMES


Regional localization of two non-specifi
✍ Donnelly, Andrew J.; Partington, Michael W.; Ryan, Anna K.; Mulley, John C. πŸ“‚ Article πŸ“… 1996 πŸ› John Wiley and Sons 🌐 English βš– 124 KB

Two genes responsible for X-linked mental retardation have been localised by linkage analysis. MRX30 maps to a 28 cM region flanked by the loci DXS990 (Xq21.3) and DXS424 (Xq24). A significant multipoint lod score of 2.78 was detected between the loci DXSll20 and DXS456. MRX31 maps to a 12 cM region

Regional localisation of a non-specific
✍ Donnelly, Andrew J. ;Choo, K. H. Andy ;Kozman, Helen M. ;Gedeon, Agi K. ;Danks, πŸ“‚ Article πŸ“… 1994 πŸ› John Wiley and Sons 🌐 English βš– 512 KB

A gene responsible for a non-specific form of X-linked mental retardation (MRxI9) was localised by linkage analysis. Exclusions and regional localisation were made using 21 highly informative PCR-based markers along the X chromosome. Significant lod scores at a recombination fraction of zero were de