Localization of non-specific X-linked mental retardation gene (MRX73) to Xp22.2
✍ Scribed by Mart�nez, Francisco ;Mart�nez-Garay, Isabel ;Mill�n, Jos� Mar�a ;P�rez-Aytes, Antonio ;Molt�, Mar�a Dolores ;Orellana, Carmen ;Prieto, F�lix
- Publisher
- John Wiley and Sons
- Year
- 2001
- Tongue
- English
- Weight
- 161 KB
- Volume
- 102
- Category
- Article
- ISSN
- 0148-7299
No coin nor oath required. For personal study only.
📜 SIMILAR VOLUMES
## Linkage analysis was performed on a fourgeneration family with nonspecific mental retardation (MRX59 ). The five affected males, ranging in age from 2 years to 52 years, have a normal facial appearance and mild to severe mental impairment. Four obligate carriers are physically normal and not ret
## Abstract Isolated mental retardation is clinically and genetically heterogenous and may be inherited in an autosomal dominant, autosomal recessive, or X‐linked manner. We report here a linkage analysis in a large family including 15 members, 6 of whom presenting X‐linked non‐syndromic mental ret
Two families with nonspecific X-linked mental retardation (XLMR) are presented. In the first family, MRX49, 5 male patients in 2 generations showed mild to moderate mental retardation. Two-point linkage analysis with 28 polymorphic markers, dispersed over the X-chromosome, yielded a maximal LOD scor
We read with interest the article, published recently in this journal by Ronce et al. [1999] describing three generations of a French family segregating with a syndromal form of X-linked mental retardation (XLMR) characterized by hypotonia, intractable seizures, and severe mental deficiency. We wish