Liver regeneration : basic mechanisms, relevant models and clinical applications

✍ Scribed by Udayan M. Apte Ph.D. DABT

Publisher: Elsevier : Academic Press
Year: 2015
Tongue: English
Leaves: 301
Edition: 1
Category: Library

No coin nor oath required. For personal study only.

✦ Synopsis

Liver Regeneration: Basic Mechanisms, Relevant Models and Clinical Applications presents cutting-edge information on liver regeneration research through an integrated, systems-wide perspective. The book addresses discoveries on hepatic progenitor cells, liver regeneration after chemical damage, and liver regeneration as a prime therapy for liver failure and disease.

By addressing the urgent need for translating basic research findings into clinically relevant modalities and potential therapeutic applications, the book provides the data needed to improve liver patient management.

Hundreds of full-color, graphic photographs and illustrations underline key elements and show researchers and students important aspects of liver transplantation, immunofluorescence, and other techniques used in liver regeneration.

Summarizes current liver regeneration studies and discussions on expected discoveries
Provides an overview of standard scientific and cutting-edge technologies to study liver regeneration
Presents details on the molecular mechanisms that affect liver regeneration
Highly illustrated, with hundreds of full-color, graphic photographs and illustrations to enhance the learning process

✦ Table of Contents

Content:
Front Matter,Copyright,Dedication,Contributors,PrefaceEntitled to full textI: IntroductionChapter 1 - Liver Regeneration: An Introduction, Pages 2-11, Udayan Apte
Chapter 2 - Models to Study Liver Regeneration, Pages 15-40, Michele T. Pritchard, Udayan Apte
Chapter 3 - Liver Regeneration in Zebrafish, Pages 41-47, Wolfram Goessling
Chapter 4 - The Priming and Progression Theory of Liver Regeneration, Pages 50-63, Kimberly J. Riehle, Kevin Riggle, Jean S. Campbell
Chapter 5 - Extracellular Signals Involved in Liver Regeneration: Direct and Auxiliary Mitogens, Pages 65-75, Udayan Apte, Pallavi B. Limaye, George K. Michalopoulos
Chapter 6 - Developmental Pathways in Liver Regeneration-I, Pages 77-101, Kari Nichole Nejak-Bowen, Satdarshan Pal Singh Monga
Chapter 7 - Mechanisms of Termination of Liver Regeneration, Pages 103-111, Chad Walesky, Udayan Apte
Chapter 8 - Role of CXC Chemokines in Liver Repair and Regeneration, Pages 113-123, Christopher M. Freeman, Gregory C. Wilson, Hiroyuki Nojima, Alex B. Lentsch
Chapter 9 - Bile Acid Receptors and Liver Regeneration, Pages 125-135, Mingjie Fan, Lili Ding, Wendong Huang
Chapter 10 - Role of Developmental Morphogens in Liver Regeneration, Pages 137-152, Mariana Verdelho Machado, Anna Mae Diehl
Chapter 11 - Regulation of Cell Cycle During Liver Regeneration, Pages 153-166, Yulia A. Nevzorova, Christian Trautwein
Chapter 12 - Changes in Hepatocyte Ploidy During Liver Regeneration, Pages 167-184, Andrew W. Duncan
Chapter 13 - Computational Modeling as an Approach to Study the Cellular and Molecular Regulatory Networks Driving Liver Regeneration, Pages 185-198, Daniel Cook, Rajanikanth Vadigepalli
Chapter 14 - Mitogen-Induced Cell Proliferation and Cancer Promotion in the Liver, Pages 199-212, Joseph Locker
Chapter 15 - Metabolic Regulation of Liver Regeneration, Pages 213-228, David A. Rudnick, Jiansheng Huang
Chapter 16 - Liver Regeneration: The Biliary Perspective, Pages 229-241, Debolina Ray, Yuyan Han, Luca Maroni, Marco Marzioni, Fanyin Meng, Gianfranco Alpini, Shannon Glaser
Chapter 17 - Introduction to Hepatic Progenitor Cells, Pages 244-253, Paulette M. Robinson, Liya Pi, Alicia R. Brown, David C. Sullivan, Bryon E. Petersen
Chapter 18 - Hepatocyte to Biliary Transdifferentiation: To Be(come) or Not to Be(come)?, Pages 255-266, Vishakha Bhave
Chapter 19 - Hepatocyte-Like Cells Derived from Pluripotent Stem Cells, Pages 267-278, Yanfeng Li, Zsuzsanna Polgar, Namita Roy-Chowdhury, Jayanta Roy-Chowdhury
Chapter 20 - Hepatic Progenitor Cell Transplantation: Relevant Models and Mechanisms, Pages 279-299, David A. Shafritz
Index, Pages 301-309

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