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CNS regeneration: basic science and clinical advances

✍ Scribed by Jeffrey H Kordower; Mark H Tuszynski


Publisher
Elsevier Academic Press
Year
2008
Tongue
English
Leaves
485
Category
Library

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✦ Synopsis


This second edition updates the burgeoning field of regeneration in the Central Nervous System (CNS) from molecular, systems, and disease-based perspective. While the book covers numerous areas in detail, special emphasis is given to discussions of movement disorders such as Parkinsons disease, Alzheimers disease, and spinal cord injury. * Incorporates information gained from cutting-edge photomicroscopy techniques Read more...

✦ Table of Contents



Content: Responses to Injury --
1. Molecular and Genetic Responses to Injury --
Larry Benowitz --
2. Glial Cells, Inflammation and CNS Trauma --
Michael T. Fitch and Jerry Silver --
Stem Cells and Trophic Factors in CNS Repair --
3. Stem Cell Therapy for Brain Tumors --
Rahul Jandial, Allen L. Ho, Michael L Levy and Evan Y. Snyder --
4. Stem Cell Therapy for Parkinson's Disease --
Andreas Androutsellis-Theotokis, Maria A. Rueger and Ron D.G. McKay --
5. Adult Neural Progenitor Cells in CNS Function and Disease --
Sebastian Jessberger, Stefan Aigner, James B. Aimone and Fred H. Gage --
6. Neurotrophic Factors --
Mark Tuszynski --
Novel Therapies for Parkinsons and Huntingtons Disease --
7. Direct Delivery of GDNF into the Non-human Primate and Human Parkinsonian Brain: Success and Road Blocks --
R. Grodin, Z. Zhang, Y. Ai, J. Slevin, A.B. Young, D.M. Gash and G.A. Gerhardt --
8. Growth Factor Gene Therapy for Parkinon's Disease --
Jeffrey H. Kordower --
9. Stimulating and Ablative Treatment for Parkinson's Disease --
Julie G. Pilitsis and Roy A.E. Bakay --
10. Neurotrophic Factor and Stem Cell Therapy for Huntington's Disease --
Jeffrey H. Kordower --
Novel Therapies for Alzheimers Disease --
11. Neurotrophic Factors and Alzheimer's Disease --
Mark Tuszynski --
12. Anti-amyloid-beta Immunotherapy as treatment for Alzheimmers Disease --
Joh R. Cirrito and David M. Holtzman --
Novel Therapies for Spinal Cord Injury and White Matter Demyelination --
13. Growth Factors for Spinal Cord Regeneration --
Mark Tuszynski --
14. Modifying the Extracellular Matrix as a Treatment to Impove Functional Recovery After Spinal Cord Injury --
James W. Fawcett --
15. Myelin Neutralization for Spinal Cord Injury and Stroke --
A.R. Walmsley, D. Bourikas and A.K. Mir --
16. Strategies to Inhibit Signaling through Nogo Receptor 1 for Spinal Cord Injury and Stroke --
Jane K. Relton and Paul H. Weinreb --
17. Cyclic AMP Modulation of Axonal Regeneration Following Spinal Cord Injury --
Sari S. Hanilla and marie T. Filbin --
18. Multiple Sclerosis: Remyelination --
Jeffery D. Kocsis, Masanori Sasaki, Karen L Lankford and Christine Radtke --
Design of Clinical Trials --
19. Clinical Trials in Rehabilitation with Neural Repair --
Bruce H. Dobkin. Intrinsic determinants of axon regeneration / Rhona Seijffers and Larry Benowitz --
Axonal responses to injury / Mike Fainzilber --
Glial cells, inflammation, and CNS trauma modulation of the inflammatory environment after injury can lead to long-distance regeneration beyond the glial scar / Michael T. Fitch and Jerry Silver --
Neurotrophic factors / Eugene M. Johnson, Jr. and Mark H. Tuszynski --
Stem cell therapy for brain tumors / Rahul Jandial ... [et al.] --
Stem cell therapies for Parkinson's disease / Andreas Androutselis-Theotokis, Maria A. Rueger, and Ron D.G. McKay --
Adult neural progenitor cells in CNS function and disease / Sebastian Jessberger ... [et al.] --
Neurotrophic factors in Alzheimer's disease / Armin Blesch and Mark H. Tuszynski --
Direct delivery of GDNF into the non-human primate and human parkinsonian brain: success and road blocks / R. Grondin ... [et al.] --
Stimulating and ablative treatment for Parkinson's disease / Julie G. Pilitsis and Roy A.E. Bakay --
Gene and cellular transplantation therapies for Huntington's disease / Shilpa Ramaswamy and Jeffrey H. Kordower --
Anti-amyloid-[beta] immunotherapy as a treatment for Alzheimer's disease / John R. Cirrito and David M. Holtzman --
Axonal plasticity and regeneration in the injured spinal cord / M.H. Tuszynski and P. Lu --
Modifying the extracellular matrix as a treatment to improve functional recovery after spinal cord injury / James W. Fawcett --
Myelin neutralization for spinal cord injury and stroke / A.R. Walmsley, D. Bourikas, and A.K. Mir --
Strategies to inhibit signaling through Nogo receptor 1 for spinal cord injury and stroke / Jane K. Relton and Paul H. Weinreb --
Cyclic AMP modulation of axonal regeneration following spinal cord injury / Sari S. Hannila and Marie T. Filbin --
Multiple sclerosis: remyelination / Jeffery D. Kocsis ... [et al.] --
Clinical trials in rehabilitation with neural repair / Bruce H. Dobkin.
Abstract:

Focuses on the field of regeneration in the Central Nervous System (CNS) from molecular, systems, and disease-based perspective. This book covers numerous areas in detail, and gives special emphasis Read more...


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