Communicated by Sauiu L.C. Woo We examined 18 unrelated individuals who have colorectal cancer or cancers associated with the HNPCC syndrome and have a family history of cancer for mutations in exon 13 of the hMSH2 gene. Two of the 18 individuals had the same previously unreported single-base delet
β¦ LIBER β¦
Linkage analysis identifies gene carriers among members of families with hereditary nonpolyposis colorectal cancer
β Scribed by A Piepoli; R Santoro; G Cristofaro; GP Traversa; M Gennarelli; L Accadia; D Siena; M Bisceglia; HT Lynch; P Peltomaki; A Andriulli
- Book ID
- 119755367
- Publisher
- Elsevier Science
- Year
- 1996
- Tongue
- English
- Weight
- 93 KB
- Volume
- 110
- Category
- Article
- ISSN
- 0016-5085
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## Abstract ## Background and Objectives The frequency of microsatellite instability (MSI) in young patients with colorectal cancer was evaluated, including reexamination of the medical and family history of each patient, and interviews with the patients to determine any possible new occurrence of
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