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Three new nonsense mutations of MLH1 and MSH2 genes in Korean families with hereditary nonpolyposis colorectal cancer

✍ Scribed by Seoyoung Yoon; Tae Sung Park; Nam Kyu Kim; Kyung-A. Lee; Juwon Kim; Jaewoo Song; Bo-Young Kim; Jong Rak Choi


Book ID
113513436
Publisher
Elsevier Science
Year
2009
Tongue
English
Weight
236 KB
Volume
188
Category
Article
ISSN
0165-4608

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## Abstract HNPCC is an autosomal dominantly inherited cancer‐susceptibility syndrome that confers an increased risk for colorectal cancer and endometrial cancer at a young age. It also entails an increased risk of a variety of other tumors, such as ovarian, gastric, uroepithelial and biliary tract