Eighteen healthy males received a single 300 mg oral dose of eprosartan as the commercial wet granulation formulation under fasting conditions and following a high-fat breakfast and a single 20 mg intravenous (i.v.) dose. The pharmacokinetics of i.v. eprosartan (mean 9 S.D.) were characterized by a
Linezolid absolute bioavailability and the effect of food on oral bioavailability
โ Scribed by Ian R. Welshman; Theresa A. Sisson; Gail L. Jungbluth; Dennis J. Stalker; Nancy K. Hopkins
- Publisher
- John Wiley and Sons
- Year
- 2001
- Tongue
- English
- Weight
- 89 KB
- Volume
- 22
- Category
- Article
- ISSN
- 0142-2782
- DOI
- 10.1002/bdd.255
No coin nor oath required. For personal study only.
๐ SIMILAR VOLUMES
Two 200mg quinidine sulfate tablets were administered to nine healthy male subjects in the fasting state, immediately after a balanced meal, and with 30ml of aluminum hydroxide gel using a complete crossover design. Serum and urine samples were taken over 32 and 60 h, respectively. Quinidine concent
Cefuroxime axetil is an ester pro-drug which permits the oral administration of cefuroxime. This study was designed to evaluate the dose proportionality of four different doses administered after a meal and to determine the absolute bioavailability of cefuroxime axetil administered with and without
Eleven healthy volunteers completed a study to compare the relative bioavailability to orally administered ciramadol in a fasting versus postprandial state. A single oral dose of 30mg of ciramadol was administered on two separate occasions, 2 weeks apart, in a randomized crossover study. A mono-or b
The objective of this study was to assess the effect of food on the pharmacokinetics of nefazodone (NEF). A group of 24 healthy adult male volunteers received a single 200 mg dose of NEF under fasting conditions as well as 5 min after a high-fat breakfast. There was a 1 week washout between treatmen
Anzemet ยฎ (dolasetron mesylate) is being developed for the prevention of chemotherapy-induced emesis and postoperative nausea and vomiting. Twenty-four healthy male subjects were orally dosed with dolasetron mesylate, 200 mg, after either an overnight fast or a high-fat breakfast. The ratio of the m