Linear Association between Cellular DNA and Epstein-Barr Virus DNA in a Human Lymphoblastoid Cell Line
✍ Scribed by Alice Adams, Tomas Lindahl and George Klein
- Book ID
- 123652078
- Publisher
- National Academy of Sciences
- Year
- 1973
- Tongue
- English
- Weight
- 845 KB
- Volume
- 70
- Category
- Article
- ISSN
- 0027-8424
- DOI
- 10.2307/63127
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## Abstract Two human lymphoblastoid cell lines were established by the transformation of human cord‐blood lymphocytes with transforming Epstein‐Barr virus (EBV). One cell line (HLB‐R1) was established with EBV obtained after the superinfection of Raji cells with HR‐1 EBV and the other (HLB‐B1) was
## Abstract The tumor promoter TPA (12‐0‐tetradecanoyl‐phorbol‐13‐acetate) efficiently induces the synthesis of Epstein‐Barr virus (EBV) antigens in EBV‐genome‐harboring human lymphoblastoid cells. We attempted to obtain information on the binding of TPA to cells and on the relationship between TPA