Immunological alteration of the Bloom's syndrome uracil DNA glycosylase in Epstein-Barr virus-transformed human lymphoblastoid cells
โ Scribed by Gita Seal; Earl E. Henderson; Michael A. Sirover
- Book ID
- 113255398
- Publisher
- Elsevier Science
- Year
- 1990
- Weight
- 633 KB
- Volume
- 243
- Category
- Article
- ISSN
- 0165-7992
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## Abstract Two human lymphoblastoid cell lines were established by the transformation of human cordโblood lymphocytes with transforming EpsteinโBarr virus (EBV). One cell line (HLBโR1) was established with EBV obtained after the superinfection of Raji cells with HRโ1 EBV and the other (HLBโB1) was
Seven lymphoblastoid cell lines were established through transformation by Epstein-Barr virus of peripheral blood lymphocytes from two patients with Bloom's syndrome (BS), the parents of a patient, and normal controls. High baseline levels of sister chromatid exchanges (SCEs) in peripheral blood lym
## Abstract The physical state of the intracellular EpsteinโBarr virus DNA was characterized in four human lymphoblastoid cell lines, Fโ265, NCโ37, Uโ303 L, and PGโ1, derived from individuals without lymphoโproliferative disease. For comparison, a previously investigated Burkitt lymphoma line, Raji