Transition of Phenotypic Dimorphism with Regard to Spontaneous Sister Chromatid Exchange in Epstein-Barr Virus-transformed Bloom's Syndrome Lymphoblastoid Cell Lines

Loss of high frequency of sister chromat

Loss of high frequency of sister chromatid exchanges in Epstein-Barr virus-established lymphoblastoid cell lines from two patients with Bloom's syndrome

✍ Tomoko Hashimoto; Shinobu Gamo; Jun-ichi Furuyama; Hide-aki Chiyo 📂 Article 📅 1983 🏛 Springer 🌐 English ⚖ 216 KB

Seven lymphoblastoid cell lines were established through transformation by Epstein-Barr virus of peripheral blood lymphocytes from two patients with Bloom's syndrome (BS), the parents of a patient, and normal controls. High baseline levels of sister chromatid exchanges (SCEs) in peripheral blood lym