Limited Sequence Heterogeneity of Epstein-Barr Virus Nuclear Antigen 1 in Benign and Malignant EBV-Associated Disorders
โ Scribed by V. Schuster, G. Ott, S. Seidenspinner, H.W. Kreth
- Book ID
- 113112139
- Publisher
- Springer-Verlag
- Year
- 2000
- Tongue
- English
- Weight
- 360 KB
- Volume
- 28
- Category
- Article
- ISSN
- 0300-8126
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๐ SIMILAR VOLUMES
A new monoclonal antibody bas been used to examine immunohistochemically the expression of the Epstein-Barr virus (EBV)encoded nuclear antigen (EBNA) 1 in virus-associated epithelial lesions. EBNAl was detected in the tumour cell nuclei of 10113 undifferentiated nasopharyngeal carcinomas and of 1011
## Abstract The elution at low pH of human EBVโpositive ^125^IโIgG bound to preparations of EBVโcarrying nonโproducer lymphoblastoid cell lines has been investigated. Specific binding was demonstrated. A number of approaches were used to confirm the specificity. The stoichiometry of binding and elu
## Abstract A quantitative assay for EBNA in human lymphoblastoid cell lines has been developed. The assay employs EBNAโpositive and โnegative ^125^IโIgG preparations as reagents and can be used in a direct or indirect manner. EBNA specificity has been demonstrated in a number of ways. The antigeni