𝔖 Bobbio Scriptorium
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Limitations of the ‘direct linear plot’ in evaluation of drug-protein binding parameters

✍ Scribed by N. Kolassa; K. Turnheim

Book ID
112659128
Publisher
Springer
Year
1976
Tongue
English
Weight
172 KB
Volume
32
Category
Article
ISSN
1420-682X

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✍ R.C. Kohberger 📂 Article 📅 1980 🏛 Elsevier Science 🌐 English ⚖ 403 KB

The efficiencies of estimates obtained from the direct linear plot (A. Cornish-Bowden and R. Eisenthal, 1978, Biochem. Biophys. Acta, 523, 268) are shown to be dependent on the spacing of substrate concentrations. When substrate values are harmonically spaced, the direct linear plot should not be us