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Usefulness of chromatographic methods for the determination of drug-protein binding parameters

✍ Scribed by Bernard Sebille; Nicole Thuaud; Jean Paul Tillement


Book ID
108334774
Publisher
Elsevier Science
Year
1980
Tongue
English
Weight
133 KB
Volume
193
Category
Article
ISSN
1873-3778

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Reversible attachment to serum proteins plays a significant role in pharmacokinetics and pharmacodynamics, and a clear understanding of this process is fundamental in the development of the rational use of many therapeutics agents. Over the last few years, it has been demonstrated that immobilized h