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Leber Hereditary Optic Neuropathy

✍ Scribed by Sadun, Alfredo A.; Sadun, Federico


Book ID
123198755
Publisher
Elsevier Science
Year
1996
Tongue
English
Weight
306 KB
Volume
103
Category
Article
ISSN
0161-6420

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This article reviews the literature on point mutation of mitochondria1 DNA (mtDNA) among Japanese and the authors' research data on pupil reaction in patients with Leber's hereditary optic neuropathy (LHON). Among Japanese, a higher frequency (80-90%) of point mutation at nucleotide position 11778 o