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Leber's Hereditary Optic Neuropathy

✍ Scribed by Rui Bi; A.-Mei Zhang; Yong-Gang Yao


Book ID
116806214
Publisher
Elsevier Science
Year
2011
Tongue
English
Weight
279 KB
Volume
118
Category
Article
ISSN
0161-6420

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This article reviews the literature on point mutation of mitochondria1 DNA (mtDNA) among Japanese and the authors' research data on pupil reaction in patients with Leber's hereditary optic neuropathy (LHON). Among Japanese, a higher frequency (80-90%) of point mutation at nucleotide position 11778 o