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Leber’s Hereditary Optic Neuropathy

✍ Scribed by Alfredo A. Sadun; Chiara La Morgia; Valerio Carelli


Book ID
107559083
Publisher
Springer
Year
2010
Tongue
English
Weight
171 KB
Volume
13
Category
Article
ISSN
1092-8480

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✍ Satoshi Ishikawa; Yoshiaki Ichibe; Junko Yokoe; Masato Wakakura 📂 Article 📅 1995 🏛 John Wiley and Sons 🌐 English ⚖ 465 KB

This article reviews the literature on point mutation of mitochondria1 DNA (mtDNA) among Japanese and the authors' research data on pupil reaction in patients with Leber's hereditary optic neuropathy (LHON). Among Japanese, a higher frequency (80-90%) of point mutation at nucleotide position 11778 o