This paper reports results of hematoporphyrin derivative based on photodynamic therapy (PDT) of 24 lung cancer lesions in 21 patients that were followed at least three months. Three of 24 lesions exhibited complete remission and 20 of 24 lesions exhibited a response to PDT. Tumors in twenty of twent
Laser and Hematoporphyrin Derivatives in Cancer
โ Scribed by Hugh-Jones, P
- Book ID
- 109835701
- Publisher
- Nature Publishing Group
- Year
- 1985
- Tongue
- English
- Weight
- 155 KB
- Volume
- 51
- Category
- Article
- ISSN
- 0007-0920
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๐ SIMILAR VOLUMES
Tbc blue-sbilicd emission from aged ~~IICOUS SO~II~~OIIS of hcmatoporphyrin and its derivatives. reporred by others to origimtc from special~ggrcg.!tcs, isshown to originate from the zinc chelates of the porphyrins. Sagestions arc made regxding the role of such zmc porphyrins in the localization of
A new photoaclrvatron mechamsm of hcmatoporphyrin dcrivatrvc IS presented This process, based on the scqucntral ab. sorption of two photons, leads to the production of cytotoxrc radicals of HpD. The cytocrdal efficnency is dcmonstmted by in vitro experiments.
Photoradiation therapy (PRT) with administration of hematoporphyrin derivative (HPD) was performed in ten cases of early stage central-type lung cancer of which six cases were treated by PRT alone due to inoperability because of poor pulmonary function in five and refusal of surgery in one. Four cas