## Abstract Both enantiomers of the six major kinds of __γ__‐lactones were synthesized to >98% e.e. in four steps, starting from succinic anhydride. The key features were the syntheses of the various __rac__‐__N__‐methyl‐4‐hydroxyalkanamides via Grignard reaction and the enantioselective acetylatio
Lactone Synthesis via Biotransformations of γ-Hydroxyamides.
✍ Scribed by Stephen K. Taylor; et al. et al.
- Publisher
- John Wiley and Sons
- Year
- 2005
- Weight
- 16 KB
- Volume
- 36
- Category
- Article
- ISSN
- 0931-7597
No coin nor oath required. For personal study only.
📜 SIMILAR VOLUMES
## Abstract For Abstract see ChemInform Abstract in Full Text.
## Abstract We have investigated 1,5‐electrocyclic ring‐closure reactions of conjugated esters with dimethyl diazomalonate in the presence of [Cu(acac)~2~] as catalyst. Our new protocol offers an easy entry to various polyfunctionalized __γ__‐lactones in high yields. Their subsequent derivatives ma
## Abstract ChemInform is a weekly Abstracting Service, delivering concise information at a glance that was extracted from about 100 leading journals. To access a ChemInform Abstract of an article which was published elsewhere, please select a “Full Text” option. The original article is trackable v
Substituted a-amino y-lactones were synthesized as potential antibacterial agents. A series of new y-substituted a-aceto and aoximino y-lactones is reported. HE OCCURRENCE of the lactone ring in many Tphysiologically active compounds has been reported throughout the literature. Of interest