Facile Synthesis of Polysubstituted Cyclopentenylamines or γ-Hydroxyamides by Samarium Diiodide.
✍ Scribed by Xiaoling Xu; Yongmin Zhang
- Publisher
- John Wiley and Sons
- Year
- 2010
- Weight
- 34 KB
- Volume
- 33
- Category
- Article
- ISSN
- 0931-7597
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✦ Synopsis
Abstract
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A simple, efficient, highly diastereoselective method for preparing (E)-α,δ-dideuterio-β,γ-unsaturated esters: SmI -promoted reduction/elimination of α-halo-β-hydroxy-γ,δ-unsaturated esters in the presence of D O. This provides the desired products in which the C-C double bond is generated with tota
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