## Abstract Lactone von L‐γ‐Hydroxyaminosäuren sind wesentliche Bausteine sämtlicher Toxine des grünen Knollenblätterpilzes (__Amanita phalloides__). Als __N__‐acylierte Derivate (**2a‐g**) racemisieren diese α‐Amino‐γ‐lactone vom Typ **1** am α‐C‐Atom bereits unter schwach basischen Bedingungen be
Synthesis of some γ-substituted α-amino γ-lactones
✍ Scribed by Fred T. Semeniuk; Metro Fedorchuk
- Publisher
- John Wiley and Sons
- Year
- 1963
- Tongue
- English
- Weight
- 370 KB
- Volume
- 52
- Category
- Article
- ISSN
- 0022-3549
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✦ Synopsis
Substituted a-amino y-lactones were synthesized as potential antibacterial agents. A series of new y-substituted a-aceto and aoximino y-lactones is reported.
HE OCCURRENCE of the lactone ring in many Tphysiologically active compounds has been reported throughout the literature. Of interest
📜 SIMILAR VOLUMES
Facile Stereoselective Synthesis of γ-Substituted γ-Amino Acids from the Corresponding α-Amino Acids. -The mild and short procedure presented is compatible with common side-chain protecting groups, sensitive functionalities and preserves the chirality of the starting α-amino acid.