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Lack of response to anakinra in rheumatoid arthritis following failure of tumor necrosis factor α blockade

✍ Scribed by Maya H. Buch; Sarah J. Bingham; Yohei Seto; Dennis McGonagle; Victoria Bejarano; Jo White; Paul Emery


Publisher
John Wiley and Sons
Year
2004
Tongue
English
Weight
56 KB
Volume
50
Category
Article
ISSN
0004-3591

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Detection of tumor necrosis factor α but
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Synovial fluids from 6 of 12 patients with rheumatoid arthritis (RA) and from 3 of 11 patients with reactive arthritis contained measurable levels of tumor necrosis factor a (TNFa). Seven of 12 sera from RA patients contained TNFa, while only 1 of those from reactive arthritis patients was positive.