Lack of IRF-1 expression in acute promyelocytic leukemia and in a subset of acute myeloid leukemias with del(5)(q31)
β Scribed by Green, WB; Slovak, ML; Chen, I-M; Pallavicini, M; Hecht, JL; Willman, CL
- Book ID
- 110054380
- Publisher
- Nature Publishing Group
- Year
- 1999
- Tongue
- English
- Weight
- 225 KB
- Volume
- 13
- Category
- Article
- ISSN
- 0887-6924
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TAL1 gene deregulation is frequent in T-cell acute lymphoblastic leukemia (T-ALL) and can result from translocations involving 1p32 or, more frequently, from a cytogenetically undetectable interstitial deletion of chromosome 1. This study presents a case of T-ALL with a t(1;5)(p32;q31) involving TAL
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