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Laboratory Practice Guidelines for Detecting and Reporting JAK2 and MPL Mutations in Myeloproliferative Neoplasms

โœ Scribed by Gong, Jerald Z.; Cook, James R.; Greiner, Timothy C.; Hedvat, Cyrus; Hill, Charles E.; Lim, Megan S.; Longtine, Janina A.; Sabath, Daniel; Wang, Y. Lynn


Book ID
123260623
Publisher
American Society for Investigative Pathology
Year
2013
Tongue
English
Weight
593 KB
Volume
15
Category
Article
ISSN
1525-1578

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โœ Tefferi, A ๐Ÿ“‚ Article ๐Ÿ“… 2010 ๐Ÿ› Nature Publishing Group ๐ŸŒ English โš– 548 KB

Myeloproliferative neoplasms (MPNs) originate from genetically transformed hematopoietic stem cells that retain the capacity for multilineage differentiation and effective myelopoiesis. Beginning in early 2005, a number of novel mutations involving Janus kinase 2 (__JAK2)__, Myeloproliferative Leuke