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Labelled psoralens. Synthesis of 4′-aminomethyltrioxsalen-3-t

✍ Scribed by Arnold A. Liebman; Charles M. Delaney

Publisher
John Wiley and Sons
Year
1981
Tongue
French
Weight
185 KB
Volume
18
Category
Article
ISSN
0022-2135

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✦ Synopsis

Abstract

Bromination of 4′‐phthalimidomethyltrioxsalen (3) provided the 3‐monobromo derivative (4) which on hydrogenolysis with either deuterium or tritium provided the corresponding labelled derivatives 5 and 6. Removal of the phthalimide moiety from 6 produced the title compound (9) having specific activity of 7.46 Ci/mmole.

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