Synthesis of New 2-Arylidene-2H-1,4-benzoxazin-3(4H)-ones. -A series of new 2-arylidenebenzoxazinones [cf. (III), (V), (VI); 10 examples in all] are synthesized by condensation of aromatic aldehydes with benzoxazinone (I). Some of the obtained compounds exhibit marked CNS depressant activity in mic
Synthesis of Furo[3,2-g][1,4]Benzoxazin-3-ones, New Psoralen Isosters
β Scribed by Adriana Chilin; Alessia Confente; Giovanni Pastorini; Adriano Guiotto
- Publisher
- John Wiley and Sons
- Year
- 2002
- Tongue
- English
- Weight
- 85 KB
- Volume
- 2002
- Category
- Article
- ISSN
- 1434-193X
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## Abstract The present review covers the synthesis and reactions of 2βheteroβ4__H__β3,1βbenzoxazinβ4βones which include oxygen, sulfur and nitrogen substituents. Literature coverage includes publications primarily from the mid 1960's to December 1999.
## Abstract Substituted 2β(benzylamino)β2__H__β1,4βbenzoxazinβ3(4__H__)βones are unstable under alkaline and acidic conditions, undergoing opening of the benzoxazinone ring. 2βBromoβ2__H__β1,4βbenzoxazinβ3(4__H__)βones show similar degradation under alkaline conditions, while replacement of Br at C