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Labeling of antibodies with 64Cu using a conjugate containing a macrocyclic amine chelating agent

โœ Scribed by Franz, J.; Freeman, G.M.; Barefield, E.K.; Volkert, W.A.; Ehrhardt, G.J.; Holmes, R.A.


Book ID
122529842
Publisher
Elsevier Science
Year
1987
Weight
680 KB
Volume
14
Category
Article
ISSN
0883-2897

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Zirconium-desferal was prepared and analysed by TLC, NMR and u.v.-spectroscopy. The stoichiometry of the complex was found to be 1:1. Chelation of desferal, coupled to resin, with 88Zr appeared to be fast and almost quantitative in various buffer systems in a broad pH-range (4-7). A high in vitro st