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l -Enantiomers of Transition State Analogue Inhibitors Bound to Human Purine Nucleoside Phosphorylase

โœ Scribed by Rinaldo-Matthis, Agnes; Murkin, Andrew S.; Ramagopal, Udupi A.; Clinch, Keith; Mee, Simon P. H.; Evans, Gary B.; Tyler, Peter C.; Furneaux, Richard H.; Almo, Steven C.; Schramm, Vern L.


Book ID
118230393
Publisher
American Chemical Society
Year
2008
Tongue
English
Weight
221 KB
Volume
130
Category
Article
ISSN
0002-7863

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Synthesis of Transition State Analogue I
โœ Gary B. Evans; Richard H. Furneaux; Graeme J. Gainsford; Vern L. Schramm; Peter ๐Ÿ“‚ Article ๐Ÿ“… 2000 ๐Ÿ› Elsevier Science ๐ŸŒ French โš– 314 KB

AbstractรSyntheses of the `Immucillins', potent aza-C-nucleoside inhibitors of purine nucleoside phosphorylase are reported as well as those of 5-deoxy-, 5-deoxyยฏuoro-and 2-deoxy-analogues and others having modiยฎed bases.