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Kisspeptin stimulation of insulin secretion: mechanisms of action in mouse islets and rats

✍ Scribed by J. E. Bowe; A. J. King; J. S. Kinsey-Jones; V. L. Foot; X. F. Li; K. T. O’Byrne; S. J. Persaud; P. M. Jones


Publisher
Springer
Year
2009
Tongue
English
Weight
211 KB
Volume
52
Category
Article
ISSN
0012-186X

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The effect of islet activating protein on glucose tolerance, insulin secretion and insulin responsiveness was studied in the NZO mouse, a model of non-insulin dependent diabetes and obesity. A single IV injection of 5 ng/g body weight islet activating protein markedly lowered plasma glucose and the