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The effect of biguanides on secretion and biosynthesis of insulin in isolated pancreatic islets of rats

โœ Scribed by H. Schatz; N. Katsilambros; C. Nierle; E. E. Pfeiffer

Publisher
Springer
Year
1972
Tongue
English
Weight
685 KB
Volume
8
Category
Article
ISSN
0012-186X

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Human islets of Langerhans were isolated from the pancreas removed from a 13-year-old female transplant donor. The islets were incubated in a culture medium for 24 h in the presence of human lymphoblastoid interferon (1000 units/ml). Insulin secretion, proinsulin biosynthesis, total protein biosynth