Clotrimazole and efaroxan stimulate insulin secretion by different mechanisms in rat pancreatic islets
β Scribed by Susan L. F. Chan; Anna L. Pallett; Noel G. Morgan
- Publisher
- Springer-Verlag
- Year
- 1997
- Tongue
- English
- Weight
- 71 KB
- Volume
- 356
- Category
- Article
- ISSN
- 0028-1298
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π SIMILAR VOLUMES
A mathematical insulin-secretion model was constructed by analyzing the glucose-induced insulin secretion using a control theory. To validate the model, experimental data obtained in the isolated rat pancreatic islet perifusion system were compared with the simulation results. The simulation study o
Insulin secretion and islet glucose metabolism were compared in pancreatic islets isolated from GK/Wistar (GK) rats with spontaneous Type 2 (non-insulin-dependent) diabetes mellitus and control Wistar rats. Islet insulin content was 24.5 +/- 3.1 microU/ng islet DNA in GK rats and 28.8 +/- 2.5 microU