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Tolbutamide stimulation and inhibition of insulin release: Studies of the underlying ionic mechanisms in isolated rat islets

โœ Scribed by J. -C. Henquin


Publisher
Springer
Year
1980
Tongue
English
Weight
889 KB
Volume
18
Category
Article
ISSN
0012-186X

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๐Ÿ“œ SIMILAR VOLUMES


The permissive effect of glucose, tolbut
โœ M. P. Hermans; W. Schmeer; J. C. Henquin ๐Ÿ“‚ Article ๐Ÿ“… 1987 ๐Ÿ› Springer ๐ŸŒ English โš– 738 KB

Mouse islets were used to study how glucose modulates arginine stimulation of insulin release. At 3 mmol/l glucose, arginine (20 mmol/l) decreased the resting membrane potential of B cells by about 10 mV, but did not evoke electrical activity. This depolarisation was accompanied by a slight but rapi