๐”– Bobbio Scriptorium
โœฆ   LIBER   โœฆ

Kinetics of repair of O6-methylguanine in DNA by O6-methylguanine-DNA methyltransferase in, vitro and in, vivo

โœ Scribed by David Scicchitano; Anthony E. Pegg

Book ID
115756264
Publisher
Elsevier Science
Year
1982
Tongue
English
Weight
375 KB
Volume
109
Category
Article
ISSN
0006-291X

No coin nor oath required. For personal study only.

๐Ÿ“œ SIMILAR VOLUMES

Differential inactivation of O6-methylgu
Differential inactivation of O6-methylguanine-dna methyltransferase activity by O6-arylmethylguanines
โœ Katsuyoshi Mineura; Masahito Fukuchi; Masayoshi Kowada; Isamu Terashima; Kohfuku ๐Ÿ“‚ Article ๐Ÿ“… 1995 ๐Ÿ› John Wiley and Sons ๐ŸŒ French โš– 473 KB

Activity of 06-methylguanine-DNA methyltransferase (MGMT) is well related with drug resistance of tumor cells to chloroethylnitrosoureas (CENUs), because MGMT removes CENU-induced O6-alkyIguanines in DNA by accepting the alkyl group at a cysteine moiety. Inactivation of MGMT is a feasible way to ove