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Kinetics of glucuronidation of phenol-derivatives of benzo(a)pyrene with rat and mouse liver microsomes

✍ Scribed by Nobuo, Nemoto; Shozo, Takayama

Book ID
123188080
Publisher
Elsevier Science
Year
1982
Tongue
English
Weight
235 KB
Volume
10
Category
Article
ISSN
0378-4274

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## Abstract Individual metabolites of benzo (a)pyrene were isolated from rat liver microsomal incubation of the parent hydrocarbon, and subsequently bound to DNA in separate incubations with microsomes. Of the metabolites examined, by far the greatest binding resulted with 7,8‐dihydro‐7,8‐dihydroxy