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Increase of liver microsomal benzo(a)pyrene monooxygenase activity by subsequent glucuronidation

✍ Scribed by K. W. Bock

Book ID
112343836
Publisher
Springer-Verlag
Year
1978
Tongue
English
Weight
263 KB
Volume
304
Category
Article
ISSN
0028-1298

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## Abstract A rat liver microsome‐mediated bacterial mutagenicity test showed 9‐hydroxybenzo (__a__) pyrene to be significantly more effective as a pre‐mutagen than benzo (__a__) pyrene. Experiments measuring the ability of these compounds to be metabolically activated to moieties that alky late ex