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Dicoumarol-sensitive glucuronidation of benzo(a)pyrene metabolites in rat liver microsomes

✍ Scribed by Juan E. Segura-Aguilar; Virginia Barreiro; Christina Lind


Book ID
115706878
Publisher
Elsevier Science
Year
1986
Tongue
English
Weight
892 KB
Volume
251
Category
Article
ISSN
0003-9861

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Rat liver microsome-mediated binding of
✍ M. H. Thompson; H. W. S. King; M. R. Osborne; P. Brookes πŸ“‚ Article πŸ“… 1976 πŸ› John Wiley and Sons 🌐 French βš– 422 KB πŸ‘ 1 views

## Abstract Individual metabolites of benzo (a)pyrene were isolated from rat liver microsomal incubation of the parent hydrocarbon, and subsequently bound to DNA in separate incubations with microsomes. Of the metabolites examined, by far the greatest binding resulted with 7,8‐dihydro‐7,8‐dihydroxy