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Kinetics of degradation in aqueous solution of Abbott-79175, a potent second generation 5-lipoxygenase inhibitor

✍ Scribed by Jay S. Trivedi; James J. Fort

Book ID
113368010
Publisher
Elsevier Science
Year
1995
Tongue
English
Weight
730 KB
Volume
123
Category
Article
ISSN
0378-5173

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Synthesis of A-79175: a second generatio
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A convergent, high yielding, and scalable synthesis of A-79175, with a key step involving a mild and efficient Cu-Pd catalyzed coupling reaction of a terminal acetylene with a substituted 2-iodofuran is discussed.