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Kinetic resolution of (R,S)-ethyl 2-hydroxyl-4-phenylbutyrate via lipase-catalyzed hydrolysis and transesterification in isooctane

โœ Scribed by Song-Hui Huang; Shau-Wei Tsai


Book ID
113803760
Publisher
Elsevier Science
Year
2004
Tongue
English
Weight
81 KB
Volume
28
Category
Article
ISSN
1381-1177

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Lipase-catalyzed irreversible transester
โœ Yi-Fong Wang; Shui-Tein Chen; Kevin K.-C. Liu; Chi-Huey Wong ๐Ÿ“‚ Article ๐Ÿ“… 1989 ๐Ÿ› Elsevier Science ๐ŸŒ French โš– 253 KB

Procedures for the resolution of several cyanohydrins of synthetic value via lipase-catalyzed kinetic resolution using enol esters as irreversible transesterification reagents are developed and the syntheses of ethyl (R)-2-hydroxy-4-phenylbutyrate and (S)-propranolol from enantiomerically pure cyano