A lipase-catalyzed enantioselective hydrolysis process under continuous in situ racemization of substrate by using trioctylamine as an organic base was developed for the production of (S)-naproxen from racemic naproxen thioesters in isooctane. Naproxen 2,2,2trifluoroethyl thioester and 45Β°C were sel
β¦ LIBER β¦
Dynamic kinetic resolution of (R, S)-naproxen 2,2,2-trifluoroethyl ester via lipase-catalyzed hydrolysis in micro-aqueous isooctane
β Scribed by Han-Yuan Lin; Shau-Wei Tsai
- Book ID
- 114396026
- Publisher
- Elsevier Science
- Year
- 2003
- Tongue
- English
- Weight
- 136 KB
- Volume
- 24-25
- Category
- Article
- ISSN
- 1381-1177
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