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Process modeling of the lipase-catalyzed dynamic kinetic resolution of (R,S)-suprofen 2,2,2-trifluoroethyl thioester in a hollow-fiber membrane

✍ Scribed by L. W. Wang; Y. C. Cheng; S. W. Tsai


Publisher
Springer
Year
2004
Tongue
English
Weight
647 KB
Volume
27
Category
Article
ISSN
1615-7605

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Lipase-catalyzed dynamic hydrolytic reso
✍ Wen-Yen Wen; I-Sin Ng; Shau-Wei Tsai 📂 Article 📅 2006 🏛 Wiley (John Wiley & Sons) 🌐 English ⚖ 177 KB

## Abstract The hydrolytic resolution of (__R__,__S__)‐2,2,2‐trifluoroethyl α‐chlorophenylacetate in water‐saturated isooctane containing Lipase MY(I) at 35 °C is selected as the best reaction condition for producing (__R__)‐α‐chlorophenyl acetic acid. The kinetic constants, and hence an enantiomer