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Kinetic and functional properties of [3H]ZM241385, a high affinity antagonist for adenosine A2A receptors

✍ Scribed by Ain Uustare; Argo Vonk; Anton Terasmaa; Kjell Fuxe; Ago Rinken

Book ID
116717776
Publisher
Elsevier Science
Year
2005
Tongue
English
Weight
270 KB
Volume
76
Category
Article
ISSN
0024-3205

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A series of novel and known 5-substituted 7-amino-2-(2-furyl) [1,2,4]triazolo [1,5a][1,3,5]triazine derivatives were synthesized and tested for adenosine receptor antagonism in radioligand binding assays at all four adenosine receptor subtypes and for inhibition of the agonist-induced cyclic AMP res