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Effect of adenosine A2A receptor antagonist ZM241385 on amygdala-kindled seizures and progression of amygdala kindling

✍ Scribed by Xiang Li; Huicong Kang; Xiaoyan Liu; Zhiguang Liu; Kai Shu; Xu Chen; Suiqiang Zhu

Book ID
113085995
Publisher
Springer-Verlag
Year
2012
Tongue
Chinese
Weight
498 KB
Volume
32
Category
Article
ISSN
0510-9752

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A competitive (NBQX) and a non-competitive (GYKI 52466) AMPA antagonist, and a competitive NMDA antagonist (D-CPPene) were tested against the development of kindling and against fully kindled seizures in amygdala-kindled rats. GYKI 52466, 10 mg/kg given i.p. 5 min prior to electrical stimulation in