A series of novel and known 5-substituted 7-amino-2-(2-furyl) [1,2,4]triazolo [1,5a][1,3,5]triazine derivatives were synthesized and tested for adenosine receptor antagonism in radioligand binding assays at all four adenosine receptor subtypes and for inhibition of the agonist-induced cyclic AMP res
β¦ LIBER β¦
Localization of adenosine A2A-receptors in rat brain with [3H]ZM-241385
β Scribed by Edward M. DeMet; Aleksandra Chicz-DeMet
- Publisher
- Springer-Verlag
- Year
- 2002
- Tongue
- English
- Weight
- 192 KB
- Volume
- 366
- Category
- Article
- ISSN
- 0028-1298
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## thio-2-propyl]-2-chloroadenosine (NNC 21-0136) is a novel adenosine agonist with neuroprotectant properties in rodent models of focal and global ischemia that exhibits diminished cardiovascular side effects when compared to reference A 1 agonists [Sheardown et al., 1995]. NNC 21-0136 is shown t