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[3H]ZM241385—an antagonist radioligand for adenosine A2A receptors in rat brain

✍ Scribed by Stephen P.H. Alexander; Paul J. Millns

Book ID
114013615
Publisher
Elsevier Science
Year
2001
Tongue
English
Weight
472 KB
Volume
411
Category
Article
ISSN
0014-2999

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A series of novel and known 5-substituted 7-amino-2-(2-furyl) [1,2,4]triazolo [1,5a][1,3,5]triazine derivatives were synthesized and tested for adenosine receptor antagonism in radioligand binding assays at all four adenosine receptor subtypes and for inhibition of the agonist-induced cyclic AMP res