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ZM 241385, an adenosine A2A receptor antagonist, inhibits hippocampal A1 receptor responses

✍ Scribed by Luı́sa V Lopes; Rodrigo A Cunha; Joaquim A Ribeiro


Book ID
114017585
Publisher
Elsevier Science
Year
1999
Tongue
English
Weight
96 KB
Volume
383
Category
Article
ISSN
0014-2999

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A series of novel and known 5-substituted 7-amino-2-(2-furyl) [1,2,4]triazolo [1,5a][1,3,5]triazine derivatives were synthesized and tested for adenosine receptor antagonism in radioligand binding assays at all four adenosine receptor subtypes and for inhibition of the agonist-induced cyclic AMP res