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Kinds of Mutations Formed When a Shuttle Vector Containing Adducts of (± )-7β ,8α -dihydroxy-9α ,10α -epoxy-7,8,9,10-tetrahydrobenzo[a]pyrene Replicates in Human Cells

✍ Scribed by Jia-Ling Yang, Veronica M. Maher and J. Justin McCormick


Book ID
123634183
Publisher
National Academy of Sciences
Year
1987
Tongue
English
Weight
988 KB
Volume
84
Category
Article
ISSN
0027-8424

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The reaction of (±)-7α, 8β-dihydroxy-9β,
✍ M. R. Osborne; P. Brookes; F. A. Beland; R. G. Harvey 📂 Article 📅 1976 🏛 John Wiley and Sons 🌐 French ⚖ 539 KB

## Abstract The reaction of (±)‐7α,8β‐dihydroxy‐9β,10β‐epoxy‐7,8,9,10‐tetrahydrobenzo(__a__)pyrene (BP diol epoxide) with DNA, followed by enzymatic hydrolysis and LH 20 Sephadex column chromatography, yielded products containing a purine deoxyribonucleoside linked to a 7,8,9,10‐tetrahydrobenzo(__a