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Metabolism of benzo[a]pyrene and 7β,8α-dihydroxy-9α,10α-epoxy-7,8,9,10-tetrahydrobenzo[a]pyrene in lung and liver of newborn mice

✍ Scribed by Assieh A. Melikian; Kourosh Bagheri; Stephen S. Hecht; Dietrich Hoffmann


Book ID
113137238
Publisher
Elsevier Science
Year
1989
Tongue
English
Weight
599 KB
Volume
69
Category
Article
ISSN
0009-2797

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## Abstract The reaction of (±)‐7α,8β‐dihydroxy‐9β,10β‐epoxy‐7,8,9,10‐tetrahydrobenzo(__a__)pyrene (BP diol epoxide) with DNA, followed by enzymatic hydrolysis and LH 20 Sephadex column chromatography, yielded products containing a purine deoxyribonucleoside linked to a 7,8,9,10‐tetrahydrobenzo(__a