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In vitro reaction of radioactive 7β,8α,-dihydroxy-9α, 10α-epoxy-7,8,9,10-tetrahydrobenzo(A)pyrene and 7β,8α-dihydroxy-9β,10β-epoxy-7,8,9,10-tetrahydrobenzo(A)pyrene with DNA

✍ Scribed by J. Remsen; D. Jerina; H. Yagi; P. Cerutti


Book ID
118312116
Publisher
Elsevier Science
Year
1977
Tongue
English
Weight
365 KB
Volume
74
Category
Article
ISSN
0006-291X

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The reaction of (±)-7α, 8β-dihydroxy-9β,
✍ M. R. Osborne; P. Brookes; F. A. Beland; R. G. Harvey 📂 Article 📅 1976 🏛 John Wiley and Sons 🌐 French ⚖ 539 KB

## Abstract The reaction of (±)‐7α,8β‐dihydroxy‐9β,10β‐epoxy‐7,8,9,10‐tetrahydrobenzo(__a__)pyrene (BP diol epoxide) with DNA, followed by enzymatic hydrolysis and LH 20 Sephadex column chromatography, yielded products containing a purine deoxyribonucleoside linked to a 7,8,9,10‐tetrahydrobenzo(__a