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Interaction of retroviruses with chemical carcinogens: Covalent binding of (±)7β,8α-dihydroxy-9α,10α,epoxy-7,8,9,10-tetrahydrobenzo[a]pyrene

✍ Scribed by Ronald M. Harris; David Kupfer; Ronald B. Luftig


Book ID
115704309
Publisher
Elsevier Science
Year
1980
Tongue
English
Weight
940 KB
Volume
204
Category
Article
ISSN
0003-9861

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✍ M. R. Osborne; P. Brookes; F. A. Beland; R. G. Harvey 📂 Article 📅 1976 🏛 John Wiley and Sons 🌐 French ⚖ 539 KB

## Abstract The reaction of (±)‐7α,8β‐dihydroxy‐9β,10β‐epoxy‐7,8,9,10‐tetrahydrobenzo(__a__)pyrene (BP diol epoxide) with DNA, followed by enzymatic hydrolysis and LH 20 Sephadex column chromatography, yielded products containing a purine deoxyribonucleoside linked to a 7,8,9,10‐tetrahydrobenzo(__a