Ketamine protects acetylcholinesterase against in vitro inhibition by sarin
β Scribed by Gertrud Puu
- Book ID
- 115780218
- Publisher
- Elsevier Science
- Year
- 1988
- Tongue
- English
- Weight
- 251 KB
- Volume
- 37
- Category
- Article
- ISSN
- 0006-2952
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In our study, we have tested six acetylcholinesterase (AChE) reactivators (pralidoxime, obidoxime, HI-6, trimedoxime, BI-6 and HlΓΆ-7) for reactivation of sarin-and cyclosarin-inhibited AChE using an in vitro reactivation test. We have used rat brain homogenate as the suitable source of enzyme. All o
## Abstract Pyridostigmine bromide (PB) has been used to protect soldiers from the toxic effects of soman, a chemical warfare agent. Recent research shows that pyridostigmine bromide protects a significant percentage of acetylcholinesterase in isolated human intercostal muscle. Findings presented h